Articles With Just Good Information

Good news from Istanbul

I am always impressed by a well-rounded acronym. It shows the research team is delighted by both science and language. In this case, we have the cumbersome An International Study of Rimonabant in Dyslipidemia with Atherogenic Risk in Abdominally Obese Patients distilled into the more convenient ADAGIO-LIPIDS. It is a shame that the team felt they had to cheat  I suppose AISRIDARAOP is not quite so catchy. Perhaps it works better in French. Two new reports based on the clinical trial of acomplia (generic name rimonabant) were presented on the 29th April in Istanbul at the 77th European Atherosclerosis Society Congress.

The first serious point to make is that ADAGIO-LIPIDS is a double-blind, randomised trial with placebo control with 799 participants run in Canada to determine whether acomplia has a beneficial effect on the level of lipids in the blood over a twelve month period. It followed on from the Rimonabant in Obesity-Lipids (RIO-LIPIDS) trial and was not intended to test whether the medication promotes weight loss. Both the test and control groups changed to a low-calorie diet before the trial began. Therefore all participants lost weight, reduced their waist measurements and increased their high-density lipoprotein (HDL) cholesterol levels before beginning their courses of medication or placebo. This allowed the trial to focus on whether acomplia changed the lipid levels of cholesterol and triglyceride in overweight patients diagnosed with atherogenic dyslipidemia ( a high-risk cardiovascular group).

After twelve months, the acomplia groups average blood pressure was reduced, the level of HDL-cholesterol increased by 7.4% and triglycerides fell 17.9%. The acomplia group also continued to lose weight and reduce their waist measurements. However, computed tomography (CT) imaging clearly demonstrated a decrease in the total visceral and subcutaneous adipose tissue. This provides scientific confirmation of previous studies which more simply recorded a reduction in waist measurements. The fatty liver index was also improved.

There is, of course, the continuing question of psychiatric side effects. In this study, all the participants were screened and only those with no history of depression or anxiety disorders were admitted. With this precaution, there was no significant difference in reported depressed moods compared with the placebo group, and the percentage of discontinuation was significantly lower than in other studies involving acomplia. For example, in the STRADIVARIUS study, about 20% of the participants were taking antidepressants before the trial began which helps to explain the significantly higher discontinuation rate.

We are therefore left with a balanced view of acomplia. As against the placebo, it produced significant improvements in the level of lipids in the blood and of fats in the body. But the potential of psychiatric side effects remains a worry  the Food and Drug Administration in the US is waiting for further evidence on the extent of the possible problems before giving approval. The fact that acomplia can produce this side effect is now well known. Consequently, the medication should only be prescribed to high-risk patients who are unable to reduce their excess weight sufficiently by modifying their diet and introducing exercise. This is the basis of the regulatory approval in Europe. Because it has the tendency to affect mood, it should not be given to people with a history of depression. Is this a significant precondition of use? Probably not. It does not seem to be any more demanding than the condition imposed on SSRI antidepressants that they should not be given to patients at risk of suicide.

The latest studies based on ADAGIO-LIPIDS confirm the beneficial effect of acomplia. This adds to an accumulating body of data suggesting that, used with care, it should be used more widely.

John Scott contributes regularly to http://www.newageweightloss.com and covers a wide range of topics including acomplia. For more information, go to http://www.newageweightloss.com/blog/good-news-from-istanbul.html.

Other Article Sites

findabook.com  moneycd.info  a-mortgage.info   about-lemon-laws.info  aboutstudentloans.info
all-about-publishing.info  auctions-articles.info  bestcollege-university.com  bestispconnection.com
biblefolder.com  blogger-website.com  books-used.info  brokers-guide.info  buywindows.info  cable-dsl.info
career-miner.com  carpel-tunnel.info  cashinaflash.info  cashloanreviews.info  casinobell.com  chat-house.info
clearmycredit.info  collegeloantips.info  crones.info  depression-articles.info   dirnic.net  dishguides.info
divers-below.com  expodog.info   financewizz.com  fire-insurance.info  getgood.info  handleit.net   it-idea.info
health-supplies.info  hosting-right.com  insidealert.com  insurance-facts.info  jobs-employment.info
justgood.info  lookgold.net   lowcost-travel.info  money-source.info  myhostzone.info  numisblog.com
peoplesearchfinder.info  pr-articles.info  realeas.com   refinancing-guides.info  spyware-remove.info
telelot.info  the-law.info   toppaid.info  travel-deals.info  travelcorrect.com  wedding-guide-site.com
your-blog.info  your-credit.info

MORE ARTICLES:

Construction Directory: News and Articles, Not Just Listings
When this writer started looking at construction directories, he found that several of them were resources with industry news and helpful articles. The same directories might also list suppliers in a conventional manner.

This Week on TelecomWeb's 'The Next Generation Contact Center Report:' News Briefs and Feature Articles
TelecomWeb's "The Next Generation Contact Center Report" features free weekly news briefs and articles geared toward helping companies migrate effectively to an IP Contact Center environment.

Earth Science News Article
Earth Science News Article

News and Emergency Information Website for California Fire Victims and Families
California fire victims and families can get News and Emergency Information at Internet websites. The websites provide links to news and information from the websites of local newspapers, TV Stations, to federal, state and local government information, and to American Red Cross sites.

This Week on TelecomWeb's "The Next Generation Contact Center Report": News Briefs and Feature Articles
Free weekly news briefs and articles geared toward helping companies migrate effectively to an IP Contact Center environment.

Zillow Article Means Positive News For Investors Buying Memphis, Tennessee Real Estate
An article produced by Zillow recently said 40% of Memphis homes were selling at a loss. Though this data was disputed by some, others say the article could shed some light on the buying opportunity that exists in the city.

New Free Information and Articles on Drug and Alcohol Addiction Presented by AddictionSearch.com
AddictionSearch has released a new site section, featuring a collection of free carefully researched articles on drug and alcohol addiction topics and issues.

Pcapex Com Pc Hardware Reviews News Amp Mods Article
Adwords Ppc Tool Adsense Affiliate Ppc Downloads First of all, provide friendly and personal information about your offer through great web contents. You can write some tips or techniques that will make their job much easier. Secondly, communicate with your customers & potential consumers through monthly ezines or newsletters. You can do this by using auto-responder. Tailored products or services may not have been a very wide option in traditional shopping which shows that interactive shopping has moved a step closer to the needs of the consumer and has improved the shopping experience in general. Internet marketing is here to stay and setting up your storefront online is surely going to bring profits for your business.

Skincare-News.com's Latest Article Discusses Facial Peels and Skin Care
Skincare-news.com explains how a facial peel can revitalize skin that has sun damage, acne, scars and even fine lines.

News Article
To write a news article is a gratifying experience for the reason that you share information with a vivacious population. When writing this sort of article, an explicit format is to be pursued. The underlying principle of this article is to express the facts of a happening to an engrossed reader.

This Week on TelecomWeb's 'The Next Generation Contact Center Report': News Briefs and Feature Articles
TelecomWeb's "The Next Generation Contact Center Report" (www.telecomweb.com/ccr) features free weekly news briefs and articles geared toward helping companies migrate effectively to an IP Contact Center environment.

This Week on TelecomWeb's "The Next-Generation Contact Center Report" -- News Briefs and Feature Articles
TelecomWeb's "The Next-Generation Contact Center Report" features free weekly news briefs and articles geared toward helping companies migrate effectively to an IP Contact Center environment.

Realty News Now - News and Information about the Real Estate Industry
The Real Estate-Focused Blog will Cover Topics such as Luxury Real Estate, Property Management, Green Building, Vacation Properties, and also Tips and Tools from Experts in the Industry.

Articles, Articles, and More Articles
Article marketing is a tried and reliable part of search engine marketing. They have become a standardized way of establishing authority, building back links, and attracting new visitors. Articles have the possibility of going viral and finding homes on blogs, ezines, or other websites, further increasing your links and exposure.